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Skin Rejuvenation

Topical skin rejuvenation is a very open field for many seeking to lure unsuspecting patients into trying new topical treatments. There are relatively few topical agents that are clinically proven to improve wrinkles and other signs of skin aging. Numerous others aren't backed by any reliable science at all and can even be harmful. As you may know, cosmetics is not regulated by the FDA. Hence it is largely up to the manufacturer's conscience not only to ensure effectiveness but safety as well. Conversely, it is up to the consumer to buy wisely.

Below is a list of the various supplements, vitamins, and chemicals that are being offered to the public in one form or another.

Clinically Proven Effective
Alpha-hydroxy Acids
Tretinoin (Retin A, Renova)
Retinoids
Estrogens
Vitamin C
Vitamin C derivatives
Anhydrous vitamin C combo

Possibly Effective but Need More Research
Palmitoyl pentapeptide-3 (Matrixyl)
Copper peptides
Alpha lipoic acid
Active retinol
Coenzyme Q10
Idebenone
Lycopene
DMAE
Green tea
MMP inhibitors
Furfuryladenine (Kinetin, Kinerase)
Progesterone
Niacinamide

Popular but Unproven
Beta-hydroxy acids
Acetyl hexapeptide-3 (Argireline)
Dermal & Soft-Tissue Fillers for Facial Rejuvenation (a.k.a. Wrinkle Fillers) 

Most wrinkles fillers are administered by injection, although few require small incisions. In some cases, wrinkle fillers are the only minimally invasive way to correct certain types of defects, such as deep folds and furrows, depressed scars or the areas of subcutaneous fat loss. However, small defects, such as fine lines or mild-to-moderate wrinkles should be treated by topical agents before treatments like fillers or lasers are considered.

Even though a few wrinkle fillers have been in use for years- the majority of them are relatively new and their long-term effects are unknown. This is partly due in part by the fact that manufacturers often try to develop new fillers based on human or animal tissue, natural biopolymers, or synthetic polymers with a history of other medical uses. Still, no wrinkle filler is ideal. Each has a unique profile of effectiveness, durability, side effects, costs, risks and uncertainties. The trick is to determine if the filler is an optimal solution in each individual situation, if so, which one is likely to be the best fit.

Noninvasive and minimally invasive skin rejuvenation procedures represent a range of choices with a minimal amount of risk. It is generally noticeable albeit a rarely dramatic improvement. These methods are worth considering if basic skin care and topically active agents are no longer sufficient yet the signs of aging you are looking to correct are still mild-to-moderate. Problems like deep wrikles or pronounced facial sag typically require more invasive methods, such as wrinkle fillers or surgery.

Invasive Rejuvenation Methods
Invasive cosmetic methods / procedures are generally for moderate-to-severe signs of aging and when a marked change is desired. Problems such as substantial facial sag or severe wrinkling are unlikely to be significantly reduced by noninvasive means. These invasive procedures tend to have longer recovery time, more short- and long-term side effects and higher costs.

It is important to understand the various procedures and their effects before undergoing any procedure. It is important to speak with your specialist to determine what the proper course of action is for you.

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